研究

<

私たちの研究活動

私たちは地域に根ざすアカデミアとして,医科学の追究とともに地域の診療水準と疾病対策の向上に貢献するエビデンスを国内外に積極的に発信することを社会的な使命と考えています。そのために本学が中心となって運営する質の高い地域コホート研究はもちろん,厚労省やAMEDなどの全国レベルの公的班研究,国際共同研究に積極的に参画し,学内外の研究者とチームを組んで研究活動を展開しています。
リアルワールドの丁寧な観察と日常の診療実践の検証を重視し、臨床的な仮説に立脚した探索的・基礎的研究へ展開してゆくことを目指しています。


主な研究資源

地域住民コホート

  1. 岩手県北地域コホート研究(Iwate KENCO study)
  2. 岩手県における東日本大震災被災者の支援を目的とした大規模コホート研究(RIAS)
  3. いわて東北メディカルメガバンク事業

全国規模健診受診者コホート

  1. 特定健診研究(The Japan Specific Health Checkups Study: J-SHC study)(厚労科研,AMED)

国際共同研究

  1. Chronic Kidney Disease Prognosis Consortium:CKD-PC(KDIGO)
  2. The Chronic Kidney Disease Outcomes and Practice Patterns Study : CKDopps(Arbor Research Collaborative for Health)


主な研究テーマ

  • 大規模コホートを用いた生活習慣病/慢性腎臓病/心血管病の発症進展の要因解析 上記1-4)
  • 慢性腎臓病の疫学の国際比較 上記4,5)
  • 腎臓病診療プラクティスと患者立脚型アウトカムの検証と国際比較 上記6)ほか
  • ゲノムワイド関連解析(GWAS)に基づく腎疾患リスクならびに治療標的の同定 上記3)
  • 腎不全における生体内レドックス制御の分子機序と治療
  • 腎不全における全身多臓器連関の病態と治療
  • 腎疾患重症化予防のための多因子治療の開発ならびに地域保健医療連携 など


研究成果
(英文論文のみ 2018年4月以降)

2023年

  • Nihei S, Ikeda T, Aoki T, Murasato F, Yaegashi M, Asahi K, Kudo K. Plasma endothelin-1 may predict bevacizumab-induced proteinuria in patients with colorectal cancer. Cancer Chemother Pharmacol. 2023; 91: 427-434.
  • Kimura Y, Yamamoto R, Shinzawa M, Aoki K, Tomi R, Ozaki S, Yoshimura R, Shimomura A, Iwatani H, Isaka Y, Iseki K, Tsuruya K, Fujimoto S, Narita I, Konta T, Kondo M, Kasahara M, Shibagaki Y, Asahi K, Watanabe T, Yamagata K, Moriyama T. Alcohol consumption and a decline in glomerular filtration rate: the Japan Specific Health Checkups study. Nutrients. 2023; 15: 1540.
  • Kosugi T, Eriguchi M, Yoshida H, Uemura T, Tasaki H, Fukata F, Nishimoto M, Matsui M, Samejima KI, Iseki K, Fujimoto S, Konta T, Moriyama T, Yamagata K, Ichiei N, Kasahara M, Shibagaki Y, Kondo M, Asahi K, Watanabe T, Tsuruya K. Height loss is associated with decreased kidney function: the Japan Specific Health Checkups (J-SHC) study. Geriatr Gerontol Int. 2023; 23: 282-288.
  • Iwasaki T, Kimura H, Tanaka K, Asahi K, Iseki K, Moriyama T, Yamagata K, Tsuruya K, Fujimoto S, Narita I, Konta T, Kondo M, Kasahara M, Shibagaki Y, Watanabe T, Kazama JJ. Association between height loss and mortality in the general population. Sci Rep. 2023; 13: 3593.
  • Mikami T, Tanno K, Sasaki R, Takanashi N, Kotozaki Y, Asahi K, Tanaka F, Omama S, Kogure M, Nakaya N, Nakamura T, Tsuchiya N, Narita A, Hozawa A, Hitomi J, Sakata K, Sasaki M. Association between the extent of house collapse and urine sodium-to-potassium ratio of victims affected by the 2011 great east Japan earthquake and tsunami: a cross-sectional study. Hypertens Res. 2023; 46: 1247-1256.
  • Kimura H, Tanaka K, Saito H, Iwasaki T, Watanabe S, Kazama S, Shimabukuro M, Asahi K, Watanabe T, Kazama JJ. Association of polypharmacy with incidence of CKD: a retrospective cohort study. Clin Exp Nephrol. 2023; 27: 272-278.
  • Saito H, Tanaka K, Iwasaki T, Oda A, Watanabe S, Kobari E, Kimura H, Kazama S, Shimabukuro M, Asahi K, Watanabe T, Kazama JJ. Hematological parameters of anemia and prognosis of non-dialysis-dependent chronic kidney disease: the Fukushima CKD cohort study. Clin Exp Nephrol. 2023; 27: 55-65.

2022年

  • Harada T, Nagai K, Mase K, Tsunoda R, Iseki K, Moriyama T, Tsuruya K, Fujimoto S, Narita I, Konta T, Kondo M, Kasahara M, Shibagaki Y, Asahi K, Watanabe T, Yamagata K. Elevated crude mortality in obese chronic kidney disease patients with loss of exercise habit: a cohort study of the Japanese general population. Intern Med. 2022 Dec 21.(Online ahead of print)
  • Otaki Y, Watanabe T, Konta T, Watanabe M, Fujimoto S, Sato Y, Asahi K, Yamagata K, Tsuruya K, Narita I, Kasahara M, Shibagaki Y, Iseki K, Moriyama T, Kondo M, Watanabe T. A body shape index and aortic disease-related mortality in Japanese general population. J Atheroscler Thromb. 2022 Sep 7.(Online ahead of print)
  • Taguchi S, Nasu T, Satoh M, Kotozaki Y, Tanno K, Tanaka F, Asahi K, Ohmomo H, Kikuchi H, Kobayashi T, Morino Y, Shimizu A, Sobue K, Sasaki M. Association between plasma xanthine oxidoreductase activity and the renal function in a general Japanese population: the Tohoku Medical Megabank community-based cohort study. Kidney Blood Press Res. 2022; 47: 722-728.
  • Kikuchi Y, Odashima Y, Yoshikawa K, Oda T, Tanaka F, Oikawa H, Ishigaki Y, Asahi K. Renal thrombotic microangiopathy and nephrotic proteinuria induced by intravitreal injection of aflibercept for diabetic macular edema. BMC Nephrol. 2022; 23: 348.
  • Kimura H, Asahi K, Tanaka K, Iseki K, Moriyama T, Yamagata K, Tsuruya K, Fujimoto S, Narita I, Konta T, Kondo M, Kasahara M, Shibagaki Y, Watanabe T, Kazama JJ. Health-related behavioral changes and incidence of chronic kidney disease: the Japan Specific Health Checkups (J-SHC) study. Sci Rep. 2022; 12: 16319.
  • Kawano K, Otaki Y, Suzuki N, Fujimoto S, Iseki K, Moriyama T, Yamagata K, Tsuruya K, Narita I, Kondo M, Shibagaki Y, Kasahara M, Asahi K, Watanabe T, Konta T. Prediction of mortality risk of health checkup participants using machine learning-based models: the J-SHC study. Sci Rep. 2022; 12: 14154.
  • Kikuchi H, Nasu T, Satoh M, Kotozaki Y, Tanno K, Asahi K, Ohmomo H, Kobayashi T, Taguchi S, Morino Y, Shimizu A, Sobue K, Sasaki M. Association between total type I collagen N-terminal propeptide and coronary artery disease risk score in the general Japanese population. Int J Cardiol Heart Vasc. 2022; 41: 101056.
  • Wakasugi M, Narita I, Iseki K, Asahi K, Yamagata K, Fujimoto S, Moriyama T, Konta T, Tsuruya K, Kasahara M, Shibagaki Y, Kondo M, Watanabe T; Japan Specific Health Checkups (J-SHC) Study Group. Healthy lifestyle and incident hypertension and diabetes in participants with and without chronic kidney disease: the Japan Specific Health Checkups (J-SHC) study. Intern Med. 2022; 61: 2841-2851.
  • Okubo R, Hoshi SL, Kimura T, Kondo M, Asahi K, Iseki C, Fujimoto S, Narita I, Nishiyama H, Yamagata K, Iseki K. Cost-effectiveness of mass screening for dipstick hematuria in Japan. Clin Exp Nephrol. 2022; 26: 398-412.
  • Oda A, Tanaka K, Saito H, Iwasaki T, Watanabe S, Kimura H, Kazama S, Shimabukuro M, Asahi K, Watanabe T, Kazama JJ. Association between serum inorganic phosphorus levels and adverse outcomes in chronic kidney disease: the Fukushima CKD cohort study. Intern Med. 2022; 61: 1653-1662.
  • Hibino M, Otaki Y, Kobeissi E, Pan H, Hibino H, Taddese H, Majeed A, Verma S, Konta T, Yamagata K, Fujimoto S, Tsuruya K, Narita I, Kasahara M, Shibagaki Y, Iseki K, Moriyama T, Kondo M, Asahi K, Watanabe T, Watanabe T, Watanabe M, Aune D. Blood pressure, hypertension, and the risk of aortic dissection incidence and mortality: results from the J-SHC study, the UK Biobank study, and a meta-analysis of cohort studies. Circulation. 2022; 145: 633-644.

2021年

  • Ogishima S, Nagaie S, Mizuno S, Ishiwata R, Iida K, Shimokawa K, Takai-Igarashi T, Nakamura N, Nagase S, Nakamura T, Tsuchiya N, Nakaya N, Murakami K, Ueno F, Onuma T, Ishikuro M, Obara T, Mugikura S, Tomita H, Uruno A, Kobayashi T, Tsuboi A, Tadaka S, Katsuoka F, Narita A, Sakurai M, Makino S, Tamiya G, Aoki Y, Shimizu R, Motoike IN, Koshiba S, Minegishi N, Kumada K, Nobukuni T, Suzuki K, Danjoh I, Nagami F, Tanno K, Ohmomo H, Asahi K, Shimizu A, Hozawa A, Kuriyama S; Tohoku Medical Megabank Project Study Group; Fuse N, Tominaga T, Kure S, Yaegashi N, Kinoshita K, Sasaki M, Tanaka H, Yamamoto M. dbTMM: an integrated database of large-scale cohort, genome and clinical data for the Tohoku Medical Megabank Project. Hum Genome Var. 2021; 8: 44.
  • Tanno K, Yonekura Y, Okuda N, Kuribayashi T, Yabe E, Tsubota-Utsugi M, Omama S, Onoda T, Ohsawa M, Ogasawara K, Tanaka F, Asahi K, Itabashi R, Ito S, Ishigaki Y, Takahashi F, Koshiyama M, Sasaki R, Fujimaki D, Takanashi N, Takusari E, Sakata K, Okayama A. Association between milk intake and incident stroke among Japanese community dwellers: the Iwate-KENCO study. Nutrients. 2021; 13: 3781.
  • Kimura H, Tanaka K, Saito H, Iwasaki T, Oda A, Watanabe S, Kanno M, Shimabukuro M, Asahi K, Watanabe T, Kazama JJ. Association of polypharmacy with kidney disease progression in adults with CKD. Clin J Am Soc Nephrol. 2021; 16: 1797-1804.
  • Otaki Y, Watanabe T, Konta T, Watanabe M, Fujimoto S, Sato Y, Asahi K, Yamagata K, Tsuruya K, Narita I, Kasahara M, Shibagaki Y, Iseki K, Moriyama T, Kondo M, Watanabe T. One-year change in diastolic blood pressure and aortic disease-related mortality in a Japanese general population aged 50-75 years. Circ J. 2021; 85: 2222-2231.
  • Matsui M, Tsuruya K, Yoshida H, Iseki K, Fujimoto S, Konta T, Moriyama T, Yamagata K, Narita I, Kasahara M, Shibagaki Y, Kondo M, Asahi K, Watanabe T. Trace proteinuria as a risk factor for cancer death in a general population. Sci Rep. 2021; 11: 16890.
  • Kosugi T, Eriguchi M, Yoshida H, Tasaki H, Fukata F, Nishimoto M, Matsui M, Samejima KI, Iseki K, Fujimoto S, Konta T, Moriyama T, Yamagata K, Narita I, Kasahara M, Shibagaki Y, Kondo M, Asahi K, Watanabe T, Tsuruya K; Japan Specific Health Checkups (J-SHC) Study Group. Association between chronic kidney disease and new-onset dyslipidemia: the Japan Specific Health Checkups (J-SHC) study. Atherosclerosis. 2021; 332: 24-32.
  • Nagai K, Yamagata K, Iseki K, Moriyama T, Tsuruya K, Fujimoto S, Narita I, Konta T, Kondo M, Kasahara M, Shibagaki Y, Asahi K, Watanabe T. Weight loss reduces the incidence of dipstick proteinuria: a cohort study from the Japanese general population. Clin Exp Nephrol. 2021; 25: 1329-1335.
  • Kikuchi Y, Tanaka F, Nakamura M, Tanno K, Onoda T, Ohsawa M, Sakata K, Omama S, Ogasawara K, Yonekura Y, Itai K, Kuribayashi T, Ishigaki Y, Okayama A, Asahi K; Iwate-Kenco Study Group. Utility of urinary albumin excretion as an index for stratifying the residual cardiovascular risk in patients undergoing antihypertensive agents treatment. J Hypertens. 2021; 39: 2431-2438.
  • Otaki Y, Watanabe T, Konta T, Watanabe M, Asahi K, Yamagata K, Fujimoto S, Tsuruya K, Narita I, Kasahara M, Shibagaki Y, Iseki K, Moriyama T, Kondo M, Watanabe T. One-year change in plasma volume and mortality in the Japanese general population: an observational cohort study. PLoS One. 2021; 16: e0254665.
  • Araumi A, Ichikawa K, Konta T, Fujimoto S, Iseki K, Moriyama T, Yamagata K, Tsuruya K, Narita I, Kondo M, Kasahara M, Shibagaki Y, Asahi K, Watanabe T. The distribution of eGFR by age in a community-based healthy population: the Japan Specific Health Checkups study (J-SHC study). Clin Exp Nephrol. 2021; 25: 1303-1310.
  • Saito H, Tanabe H, Kudo A, Machii N, Higa M, Yamaguchi S, Maimaituxun G, Abe K, Takahashi A, Tanaka K, Asahi K, Masuzaki H, Ohira H, Kazama JJ, Shimabukuro M. High FIB4 index is an independent risk factor of diabetic kidney disease in type 2 diabetes. Sci Rep. 2021; 11: 11753.
  • Nishimoto M, Murashima M, Yoshida H, Eriguchi M, Tasaki H, Fukata F, Kosugi T, Matsui M, Samejima KI, Iseki K, Asahi K, Yamagata K, Fujimoto S, Konta T, Narita I, Moriyama T, Kasahara M, Shibagaki Y, Kondo M, Watanabe T, Tsuruya K; Japan Specific Health Checkups (J-SHC) Study Group. Impact of self-reported walking habit on slower decline in renal function among the general population in a longitudinal study: the Japan Specific Health Checkups (J-SHC) Study. J Nephrol. 2021; 34: 1845-1853.
  • Otaki Y, Konta T, Ichikawa K, Fujimoto S, Iseki K, Moriyama T, Yamagata K, Tsuruya K, Narita I, Kondo M, Shibagaki Y, Kasahara M, Asahi K, Watanabe T. Possible burden of hyperuricaemia on mortality in a community-based population: a large-scale cohort study. Sci Rep. 2021; 11: 8999.
  • Hoshino J, Tsunoda R, Nagai K, Kai H, Saito C, Ito Y, Asahi K, Kondo M, Iseki K, Iseki C, Okada H, Kashihara N, Narita I, Wada T, Combe C, Pisoni RL, Robinson BM, Yamagata. Comparison of annual eGFR decline among primary kidney diseases in patients with CKD G3b-5: results from a REACH-J CKD cohort study. Clin Exp Nephrol. 2021; 25: 902-910.
  • Nagai K, Asahi K, Iseki K, Yamagata K. Estimating the prevalence of definitive chronic kidney disease in the Japanese general population. Clin Exp Nephrol. 2021; 25:885-892.
  • Otaki Y, Watanabe T, Konta T, Watanabe M, Asahi K, Yamagata K, Fujimoto S, Tsuruya K, Narita I, Kasahara M, Shibagaki Y, Iseki K, Moriyama T, Kondo M, Watanabe T. Impact of chronic kidney disease on aortic disease-related mortality: a four-year community-based cohort study. Intern Med. 2021; 60: 689-697.
  • Wakasugi M, Narita I, Iseki K, Asahi K, Yamagata K, Fujimoto S, Moriyama T, Konta T, Tsuruya K, Kasahara M, Shibagaki Y, Kondo M, Watanabe T. The effect of CKD on associations between lifestyle factors and all-cause, cancer, and cardiovascular mortality: a population-based cohort study. Intern Med. 2021; 60: 2189-2200.
  • Saito H, Tanaka K, Iwasaki T, Oda A, Watanabe S, Kanno M, Kimura H, Shimabukuro M, Asahi K, Watanabe T, Kazama JJ. Xanthine oxidase inhibitors are associated with reduced risk of cardiovascular disease. Sci Rep. 2021; 11: 1380.
  • Iwasaki M, Kudo A, Asahi K, Machii N, Iseki K, Satoh H, Moriyama T, Yamagata K, Tsuruya K, Fujimoto S, Narita I, Konta T, Kondo M, Shibagaki Y, Kasahara M, Watanabe T, Shimabukuro M. Fast walking is a preventive factor against new-onset diabetes mellitus in a large cohort from a Japanese general population. Sci Rep. 2021; 11: 716.
  • Tanaka K, Saito H, Iwasaki T, Oda A, Watanabe S, Kanno M, Kimura H, Shimabukuro M, Asahi K, Watanabe T, Kazama JJ. Association between serum potassium levels and adverse outcomes in chronic kidney disease: the Fukushima CKD cohort study. Clin Exp Nephrol. 2021 Jan 7.
  • Iseki K, Konta T, Asahi K, Yamagata K, Fujimoto S, Tsuruya K, Narita I, Kasahara M, Shibagaki Y, Moriyama T, Kondo M, Watanabe T. Higher cardiovascular mortality in men with persistent dipstick hematuria. Clin Exp Nephrol. 2021; 25: 150-156.
  • Hatano Y, Yano Y, Fujimoto S, Sato Y, Iseki K, Konta T, Moriyama T, Yamagata K, Tsuruya K, Narita I, Kondo M, Kasahara M, Shibagaki Y, Asahi K, Watanabe T. The population-attributable fraction for premature mortality due to cardiovascular disease associated with stage 1 and 2 hypertension among Japanese. Am J Hypertens. 2021; 34: 56-63.

2020年

  • Matsuura Y, Tanaka F, Segawa T, Tanno K, Sakata K, Ohsawa M, Omama S, Ogasawara K, Asahi K, Nakamura M. Sex differences in the influence of elevated serum uric acid levels for cardiovascular risk in the general population with normal renal function. J Iwate Med Assoc. 2020; 72:145-155.
  • Osaki T, Satoh M, Tanaka F, Tanno K, Takahashi Y, Nasu T, Sakata K, Morino Y, Sobue K, Sasaki M: The Value of a Cystatin C-based Estimated Glomerular Filtration Rate for Cardiovascular Assessment in a General Japanese Population: Results From the Iwate Tohoku Medical Megabank Project. J Epidemiol. 2020; 30: 260-267.
  • Hoshino J, Muenz D, Zee J, Sukul N, Speyer E, Guedes M, Lopes AA, Asahi K, van Haalen H, James G, Dhalwani N, Pecoits-Filho R, Bieber B, Robinson BM, Pisoni RL; CKDopps Investigators. Associations of Hemoglobin Levels With Health- Related Quality of Life, Physical Activity, and Clinical Outcomes in Persons With Stage 3-5 Nondialysis CKD. J Ren Nutr. 2020; 30: 404-414.
  • Otaki Y, Watanabe T, Konta T, Watanabe M, Asahi K, Yamagata K, Fujimoto S, Tsuruya K, Narita I, Kasahara M, Shibagaki Y, Iseki K, Moriyama T, Kondo M, Watanabe T. Impact of hyperuricemia on mortality related to aortic diseases: a 3.8-year nationwide community-based cohort study. Sci Rep. 2020; 10: 14281.
  • Otaki Y, Watanabe T, Konta T, Watanabe M, Asahi K, Yamagata K, Fujimoto S, Tsuruya K, Narita I, Kasahara M, Shibagaki Y, Iseki K, Moriyama T, Kondo M, Watanabe T. Impact of calculated plasma volume status on all-cause and cardiovascular mortality: 4-year nationwide community-based prospective cohort study. PLoS One. 2020; 15: e0237601.
  • Sato Y, Fujimoto S, Iseki K, Konta T, Moriyama T, Yamagata K, Tsuruya K, Narita I, Kondo M, Kasahara M, Shibagaki Y, Asahi K, Watanabe T. Higher baseline uric acid concentration is associated with non-attainment of optimal blood pressure. PLoS One. 2020; 15: e0236602.
  • Iseki K, Konta T, Asahi K, Yamagata K, Fujimoto S, Tsuruya K, Narita I, Kasahara M, Shibagaki Y, Moriyama T, Kondo M, Iseki C, Watanabe T. Impact of Metabolic Syndrome on the Mortality Rate among Participants in a Specific Health Check and Guidance Program in Japan. Intern Med. 2020; 59: 2671-2678.
  • Tanabe H, Saito H, Kudo A, Machii N, Hirai H, Maimaituxun G, Tanaka K, Masuzaki H, Watanabe T, Asahi K, Kazama J, Shimabukuro M. Factors Associated with Risk of Diabetic Complications in Novel Cluster-Based Diabetes Subgroups: A Japanese Retrospective Cohort Study. J Clin Med. 2020; 9: 2083.
  • Tanabe H, Saito H, Machii N, Kudo A, Tanaka K, Asahi K, Kazama JJ, Shimabukuro M. Burden of Undiagnosed Type 2 Diabetes in Diabetic Kidney Disease: A Japanese Retrospective Cohort Study. J Clin Med. 2020; 9: 2028.
  • Tanaka F, Komi R, Nakamura M, Tanno K, Onoda T, Ohsawa M, Sakata K, Omama S, Ogasawara K, Ishibashi Y, Yonekura Y, Itai K, Kuribayashi T, Kikuchi Y, Ishigaki Y, Okayama A, Asahi K; Iwate-Kenco Study Group. Additional prognostic value of electrocardiographic left ventricular hypertrophy in traditional cardiovascular risk assessments in chronic kidney disease. J Hypertens. 2020; 38: 1149-1157.
  • Ikeda T, Inoue S, Konta T, Murakami M, Fujimoto S, Iseki K, Moriyama T, Yamagata K, Tsuruya K, Narita I, Kondo M, Shibagaki Y, Kasahara M, Asahi K, Watanabe T. Can Daily Walking Alone Reduce Pneumonia-Related Mortality among Older People? Sci Rep. 2020; 10: 8556.
  • Nakajima A, Tanaka K, Saito H, Iwasaki T, Oda A, Kanno M, Shimabukuro M, Asahi K, Watanabe T, Kazama JJ. Blood pressure control in chronic kidney disease according to underlying renal disease: the Fukushima CKD cohort. Clin Exp Nephrol. 2020; 24: 427-434.
  • Konta T, Ichikawa K, Kawasaki R, Fujimoto S, Iseki K, Moriyama T, Yamagata K, Tsuruya K, Narita I, Kondo M, Shibagaki Y, Kasahara M, Asahi K, Watanabe T. Association between serum uric acid levels and mortality: a nationwide community-based cohort study. Sci Rep. 2020; 10: 6066.

2019年

  • Nagai K, Yamagata K, Iseki K, Moriyama T, Tsuruya K, Fujimoto S, Narita I, Konta T, Kondo M, Kasahara M, Shibagaki Y, Asahi K, Watanabe T. Antihypertensive treatment and risk of cardiovascular mortality in patients with chronic kidney disease diagnosed based on the presence of proteinuria and renal function: A large longitudinal study in Japan. PLoS One. 2019; 14: e0225812.
  • Nagai K, Yamagata K, Iseki K, Moriyama T, Tsuruya K, Fujimoto S, Narita I, Konta T, Kondo M, Kasahara M, Shibagaki Y, Asahi K, Watanabe T: Cause-specific mortality in the general population with transient dipstick-proteinuria. PLoS One. 2019; 14: e0223005.
  • Nishimoto M, Tagawa M, Matsui M, Eriguchi M, Samejima KI, Iseki K, Iseki C, Asahi K, Yamagata K, Konta T, Fujimoto S, Narita I, Kasahara M, Shibagaki Y, Moriyama T, Kondo M, Watanabe T, Tsuruya K: A prediction model with lifestyle in addition to previously known risk factors improves its predictive ability for cardiovascular death. Sci Rep. 2019; 9: 12953.
  • Takahashi Y, Satoh M, Ohmomo H, Tanaka F, Osaki T, Tanno K, Nasu T, Sakata K, Morino Y, Sobue K, Sasaki M: Association between high-sensitivity cardiac troponin T and future cardiovascular incidence in a general Japanese population: results from the Tohoku medical megabank project. Biomarkers. 2019; 24: 566-573.
  • Uchida D, Kido R, Kawarazaki H, Murasawa M, Ando A, Fujimoto S, Iseki K, Moriyama T, Yamagata K, Tsuruya K, Konta T, Narita I, Kondo M, Kasahara M, Asahi K, Watanabe T, Shibagaki Y: Lower diastolic blood pressure was associated with higher incidence of chronic kidney disease in the general population only in those using antihypertensive medications. Kidney Blood Press Res. 2019; 44: 973-983.
  • Nagai K, Iseki C, Iseki K, Kondo M, Asahi K, Saito C, Tsunoda R, Okubo R, Yamagata K: Higher medical costs for CKD patients with a rapid decline in eGFR: a cohort study from the Japanese general population. PLoS One. 2019; 14: e0216432.
  • Sukul N, Speyer E, Tu C, Bieber BA, Li Y, Lopes AA, Asahi K, Mariani L, Laville M, Rayner HC, Stengel B, Robinson BM, Pisoni RL; CKDopps and CKD-REIN investigators: Pruritus and patient reported outcomes in non-dialysis CKD. Clin J Am Soc Nephrol. 2019; 14: 673-681.
  • Sakamoto M, Edo N, Takahashi S, Okamura E, Uno K, Morita K, Ishikawa T, Asahi K, Iseki K, Moriyama T, Yamagata K, Tsuruya K, Fujimoto S, Narita I, Konta T, Kondo M, Kimura K, Ohashi Y, Watanabe T, Tsukamoto K: Association between prescription and control status of dyslipidemia and hypertension among Japanese patients with diabetes. J Atheroscler Thromb. 2019; 26: 805-820.
  • Hirai H, Asahi K, Yamaguchi S, Mori H, Satoh H, Iseki K, Moriyama T, Yamagata K, Tsuruya K, Fujimoto S, Narita I, Konta T, Kondo M, Shibagaki Y, Kasahara M, Watanabe T, Shimabukuro M. New risk prediction model of coronary heart disease in participants with and without diabetes: Assessments of the Framingham risk and Suita scores in 3-year longitudinal database in a Japanese population. Sci Rep. 2019; 9: 2813.
  • Okada H, Yasuda Y, Kashihara N, Asahi K, Tanaka K, et al. Essential points from Evidence-based Clinical Practice Guidelines for Chronic Kidney Disease 2018. Clin Exp Nephrol. 2019; 23: 1-15.

2018年

  • Otaki Y, Watanabe T, Konta T, Watanabe M, Fujimoto S, Sato Y, Asahi K, Yamagata K, Tsuruya K, Narita I, Kasahara M, Shibagaki Y, Iseki K, Moriyama T, Kondo M, Watanabe T. Effect of Hypertension on Aortic Artery Disease-Related Mortality - 3.8-Year Nationwide Community-Based Prospective Cohort Study. Circ J. 2018; 82: 2776-2782.
  • Ogata E, Asahi K, Yamaguchi S, Iseki K, Sato H, Moriyama T, Yamagata K, Tsuruya K, Fujimoto S, Narita I, Konta T, Kondo M, Shibagaki Y, Kasahara M, Watanabe T, Shimabukuro M. Low fasting plasma glucose level as a predictor of new-onset diabetes mellitus on a large cohort from a Japanese general population. Sci Rep. 2018 Sep 17; 8:13927.
  • Tanaka K, Tanaka F, Onoda T, Tanno K, Ohsawa M, Sakata K, Omama S, Ogasawara K, Ishibashi Y, Itai K, Kuribayashi T, Okayama A, Nakamura M; Iwate-Kenco Study Group. Prognostic Value of Electrocardiographic Left Ventricular Hypertrophy on Cardiovascular Risk in a Non-Hypertensive Community-Based Population. Am J Hypertens. 2018; 31: 895-901.
  • Komi R, Tanaka F, Omama S, Ishibashi Y, Tanno K, Onoda T, Ohsawa M, Tanaka K, Okayama A, Nakamura M; Iwate-Kenco Study Group. Burden of high blood pressure as a contributing factor to stroke in the Japanese community-based diabetic population. Hypertens Res. 2018; 41: 531-538.


受賞

  • 2023年9月に仙台市で開催されました第53回日本腎臓学会東部学術大会にて、赤坂祐一郎医師がプログラム医院長賞を受賞しました。
    受賞演題:エルドハイム・チェスター病に発生したネフローゼ症候群の一例
  • 菊池調助教の研究が、大和証券ヘルス財団の令和4年度調査研究費助成を受領いたしました。
    研究課題:大規模住民コホートデータを活用した循環器疾患の長期的危険要因の性差に関する研究
    大和証券ヘルス財団贈呈式
    盛岡タイムス2022年12月1日付記事
  • 2022年6月に神戸市で開催されました第65回日本腎臓学会学術総会にて、松浦佑樹医師が優秀論文賞を受賞いたしました。
    受賞論文:First case report of monoclonal IgG3-heavy-chain glomerulonephritis with microtubular structures【CEN Case Reports(2021)10:236-240】

トップに戻る
トップに戻る